Decreased serum levels of kisspeptin in early pregnancy are associated with intra-uterine growth restriction and pre-eclampsia.

@article{Armstrong2009DecreasedSL,
  title={Decreased serum levels of kisspeptin in early pregnancy are associated with intra-uterine growth restriction and pre-eclampsia.},
  author={Roisin A Armstrong and Rebecca M. Reynolds and Rosemary Leask and Catherine H Shearing and Andrew A. Calder and Simon C. Riley},
  journal={Prenatal diagnosis},
  year={2009},
  volume={29 10},
  pages={982-5}
}
OBJECTIVE To investigate whether pregnancies with development of subsequent pre-eclampsia and intra-uterine growth restriction are associated with altered levels of kisspeptin in maternal serum in the second trimester. STUDY DESIGN Retrospective case-control study of 16-20 week serum samples matched for duration of storage at -70 degrees C. Levels of kisspeptin were measured in serum from women with pregnancies with subsequent development of pre-eclampsia (n = 57), intra-uterine growth… CONTINUE READING

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