Decreased serotonin2A receptors in Brodmann's area 9 from schizophrenic subjects. A pathological or pharmacological phenomenon?

@article{Dean1998DecreasedSR,
  title={Decreased serotonin2A receptors in Brodmann's area 9 from schizophrenic subjects. A pathological or pharmacological phenomenon?},
  author={Brian Dean and Wendy Hayes and Ceredwyn Elizabeth Hill and David Leon Copolov},
  journal={Molecular and chemical neuropathology},
  year={1998},
  volume={34 2-3},
  pages={133-45}
}
There have been repeated reports of a decrease in serotonin2A receptors in the frontal cortex from subjects with schizophrenia. Similarly, in rats treated with antipsychotic drugs, it has been shown that many antipsychotic drugs decrease cortical serotonin2A receptors, an affect not seen with the antipsychotic drug haloperidol. We therefore compared the density of serotonin2A receptors in frontal cortex from schizophrenic subjects treated with haloperidol, schizophrenic subjects treated with… CONTINUE READING

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