Decreased renal clearance of digoxin in chronic congestive heart failure

@article{Naafs2004DecreasedRC,
  title={Decreased renal clearance of digoxin in chronic congestive heart failure},
  author={M. A. Naafs and C. V. D. Hoek and S. V. Duin and G. Koorevaar and W. Schopman and J. Silberbusch},
  journal={European Journal of Clinical Pharmacology},
  year={2004},
  volume={28},
  pages={249-252}
}
SummaryRenal digoxin clearance was compared in patients suffering from atrial fibrillation with well preserved cardiac function (n=9; salt intake ±170 mmol daily) and patients with chronic congestive heart failure (n=10; salt intake 50 mmol daily and maintenance treatment with diuretics). There was no difference between the groups concering digoxin dosage, creatinine clearance, diuresis or sodium excretion in the urine. Digoxin clearance in chronic heart failure proved to be significantly lower… Expand
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