Decreased pulmonary vasoreactivity in an animal model of chronic Pseudomonas pneumonia.

@article{Graham1990DecreasedPV,
  title={Decreased pulmonary vasoreactivity in an animal model of chronic Pseudomonas pneumonia.},
  author={Lisa M. Graham and Adriana I. Vasil and Michael L. Vasil and Norbert Felix Voelkel and Kurt R Stenmark},
  journal={The American review of respiratory disease},
  year={1990},
  volume={142 1},
  pages={221-9}
}
Chronic pulmonary infection/colonization caused by Pseudomonas aeruginosa accounts for much of the morbidity and mortality in cystic fibrosis (CF). The effect of chronic pulmonary P. aeruginosa infection on the pulmonary circulation has not been studied. Therefore, we investigated the effect of chronic P. aeruginosa infection on pulmonary hemodynamics in a rat model. Two groups of rats were inoculated with either agar beads containing 1.0 x 10(4) colony-forming units of P. aeruginosa (infected… CONTINUE READING
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