Decreased pulmonary inflammation after ethanol exposure and burn injury in intercellular adhesion molecule-1 knockout mice.

@article{Bird2010DecreasedPI,
  title={Decreased pulmonary inflammation after ethanol exposure and burn injury in intercellular adhesion molecule-1 knockout mice.},
  author={Melanie D Bird and Michelle O Morgan and Luis Enrique Soto Ram{\'i}rez and Sherri Yong and Elizabeth J. Kovacs},
  journal={Journal of burn care & research : official publication of the American Burn Association},
  year={2010},
  volume={31 4},
  pages={652-60}
}
Clinical and laboratory evidence suggests that alcohol consumption dysregulates immune function. Burn patients who consume alcohol before their injuries demonstrate higher rates of morbidity and mortality, including acute respiratory distress syndrome, than patients without alcohol at the time of injury. Our laboratory observed higher levels of proinflammatory cytokines and leukocyte infiltration in the lungs of mice after ethanol exposure and burn injury than with either insult alone. To… CONTINUE READING

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