Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease.

@article{Guan2000DecreasedPL,
  title={Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease.},
  author={Zhi-Zhong Guan and Xiao Zhang and Rivka G. Ravid and A. Nordberg},
  journal={Journal of neurochemistry},
  year={2000},
  volume={74 1},
  pages={237-43}
}
Deficits of cortical nicotinic acetylcholine receptors (nAChRs) have been observed in Alzheimer's disease (AD) by receptor binding assays. Little is known about the receptor subunit specificity influenced by AD, and it might be of importance for therapeutic strategies. In the present study, the protein levels of nAChR alpha3, alpha4, alpha7, and beta2… CONTINUE READING