Decreased protection by HDL from poorly controlled type 2 diabetic subjects against LDL oxidation may Be due to the abnormal composition of HDL.

@article{Gowri1999DecreasedPB,
  title={Decreased protection by HDL from poorly controlled type 2 diabetic subjects against LDL oxidation may Be due to the abnormal composition of HDL.},
  author={M S Gowri and Deneys R. van der Westhuyzen and S. R. Bridges and James W. Anderson},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1999},
  volume={19 9},
  pages={2226-33}
}
High plasma triglyceride concentrations in diabetic subjects increase their risk for developing coronary heart disease. Numerous studies have shown that the high density lipoprotein (HDL) composition is abnormal in type 2 diabetic subjects. One study has shown that HDL (lipoprotein A-I) isolated from subjects with non-insulin-dependent diabetes mellitus exhibits a decreased capacity to induce cholesterol efflux. The current study examined the effect of HDL(2) and HDL(3) subfractions from poorly… CONTINUE READING

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