Decreased plasma tryptophan in pregnancy.

  title={Decreased plasma tryptophan in pregnancy.},
  author={Hans Schr{\"o}cksnadel and Gabriele Baier-Bitterlich and Otto Dapunt and Helmut Wachter and Dietmar Fuchs},
  journal={Obstetrics and gynecology},
  volume={88 1},
OBJECTIVE To examine levels of serum tryptophan and its degradation product kynurenine in uncomplicated pregnancy, according to the week of pregnancy and the concentrations of neopterin. METHODS Plasma was analyzed from 45 healthy pregnant women (15 in each trimester), 15 healthy puerperas, and 20 nonpregnant controls. Tryptophan and kynurenine were measured by reverse-phase, high-performance liquid chromatography, and neopterin by radioimmunoassay. RESULTS In healthy pregnant women… CONTINUE READING