Decreased plasma levels of IL-33 could contribute to the altered function of Th2 lymphocytes in patients with polycythemia vera and essential thrombocythemia.

@article{Gangemi2013DecreasedPL,
  title={Decreased plasma levels of IL-33 could contribute to the altered function of Th2 lymphocytes in patients with polycythemia vera and essential thrombocythemia.},
  author={Sebastiano Gangemi and Alessandro Allegra and Mirella Profita and Salvatore Saitta and Demetrio Gerace and Anna Bonanno and Andrea Alonci and Annamaria Petrungaro and Sabina Russo and Caterina Musolino},
  journal={Cancer investigation},
  year={2013},
  volume={31 3},
  pages={212-3}
}
To the Editor: Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms (MPNs) primarily characterized by erythrocytosis and thrombocytosis, respectively (1). In addition, quality of life is adversely affected by a spectrum of disease complications including pruritus. Interleukin-33 (IL-33) is a cytokine from the IL-1 family, which has been linked to important diseases, including asthma, rheumatoid arthritis, ulcerative colitis, metabolic, neurologic, and… CONTINUE READING

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