Decreased paraoxonase 1, arylesterase enzyme activity, and enhanced oxidative stress in patients with mitral and aortic valve insufficiency.

@article{Yilmaz2013DecreasedP1,
  title={Decreased paraoxonase 1, arylesterase enzyme activity, and enhanced oxidative stress in patients with mitral and aortic valve insufficiency.},
  author={Necat S Yilmaz and Nevin Şimşek and Ozgur Aydin and Emirhan Yardan and Sakir Aslan and Esin Eren and Ayşenur Yeğin and Sadik Buyukbas},
  journal={Clinical laboratory},
  year={2013},
  volume={59 5-6},
  pages={
          597-604
        }
}
BACKGROUND Oxidative stress is reportedly associated with several cardiovascular diseases. The antioxidant ability of high density lipoprotein (HDL) is, at least in part, attributable to the pleiotropic serum paraoxonase (PON1). The aim of the study was to investigate the body oxidant/antioxidant balance in patients with mitral regurgitation (MR) and aortic regurgitation (AR) to get new points of view for the underlying oxidative mechanisms. METHODS Oxidative stress index (OSI), total oxidant… CONTINUE READING
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