Decreased osteoprotegerin and increased bone turnover in young female patients with major depressive disorder and a lifetime history of anorexia nervosa

@article{Kahl2004DecreasedOA,
  title={Decreased osteoprotegerin and increased bone turnover in young female patients with major depressive disorder and a lifetime history of anorexia nervosa},
  author={Kai G. Kahl and Sebastian Rudolf and Leif Dibbelt and Beate Maria Stoeckelhuber and Hans-Bj{\"o}rn Gehl and Fritz Hohagen and Ulrich Schweiger},
  journal={Osteoporosis International},
  year={2004},
  volume={16},
  pages={424-429}
}
Low bone mineral density (BMD) is a frequent, often persistent complication in patients with major depressive disorder (MDD) and anorexia nervosa (AN) that increases the risk of pathologic fractures. The pathogenetic process underlying osteopenia in MDD and AN is still unclear, although several factors, including a dysbalance of cytokines, are associated with loss of bone mass. Alterations in the serum levels of cytokines have been observed in patients with MDD, AN, and other psychiatric… CONTINUE READING