Decreased natural killer cell responses and altered interleukin-6 and interleukin-10 production in alcoholism: an interaction between alcohol dependence and African-American ethnicity.

@article{Irwin2000DecreasedNK,
  title={Decreased natural killer cell responses and altered interleukin-6 and interleukin-10 production in alcoholism: an interaction between alcohol dependence and African-American ethnicity.},
  author={Michael R. Irwin and Charles Miller},
  journal={Alcoholism, clinical and experimental research},
  year={2000},
  volume={24 4},
  pages={560-9}
}
BACKGROUND Epidemiological data indicate that among alcoholics African-American men have higher rates of infections compared with white alcoholics. Alcohol is thought to reduce natural killer (NK) cell responses and to alter cellular immunity by changing the relative balance of Th1 versus Th2 cytokine response profiles. However, translation of these basic immunological observations into the clinical setting is limited, and what clinical data are available are contradictory, in part, because of… CONTINUE READING

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