Decreased mitochondrial oxidation of fatty acids in pregnant mice: possible relevance to development of acute fatty liver of pregnancy.

@article{Grimbert1993DecreasedMO,
  title={Decreased mitochondrial oxidation of fatty acids in pregnant mice: possible relevance to development of acute fatty liver of pregnancy.},
  author={Sylvie Grimbert and Bernard Fromenty and Caroline Fisch and Philippe Lett{\'e}ron and Alain Berson and Anne-Marie Durand-Schneider and G{\'e}rard Feldmann and Dominique Pessayre},
  journal={Hepatology},
  year={1993},
  volume={17 4},
  pages={628-37}
}
Severe impairment of the beta-oxidation of fatty acids, as a consequence of a single factor or a combination of different causes, leads to microvesicular steatosis of the liver. In an effort to understand the mechanism(s) leading to the development of acute fatty liver of pregnancy in some women, we determined the effects of pregnancy on the mitochondrial oxidation of fatty acids in mice. In vivo, the rate of oxidation of the whole fatty-acid chain length was determined by measuring the rate of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

Similar Papers

Loading similar papers…