Decreased membrane fluidity during differentiation of human promyelocytic leukemia cells in culture.

@article{Ip1980DecreasedMF,
  title={Decreased membrane fluidity during differentiation of human promyelocytic leukemia cells in culture.},
  author={Stephen H. Ip and Richard A. Cooper},
  journal={Blood},
  year={1980},
  volume={56 2},
  pages={227-32}
}
The human promyelocytic leukemia cell line. HL-60. undergoes differentiation in the presence of dimethyl sulfoxide (DMSO). phorbol esters, and other agents. Studies were undertaken to determine whether agents that promote differentiation influence membrane fluidity and to assess whether changes in membrane fluidity occur during the process of differentiation. Cells were grown in the presence of DMSO, 1 .25%. or tetradecanolyl-phorbol 1 3-acetate (TPA). 1 .6 x 10 5M. Surface membranes were… CONTINUE READING

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