Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing.

@article{Maruyama2007DecreasedMN,
  title={Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing.},
  author={Kazuichi Maruyama and Jun Asai and Masaaki and Tina M. Thorne and Douglas W. Losordo and Patricia A D'Amore},
  journal={The American journal of pathology},
  year={2007},
  volume={170 4},
  pages={1178-91}
}
Impaired wound healing is a common complication of diabetes. Although it is well known that both macrophages and blood vessels are critical to wound repair, the role of wound-associated lymphatic vessels has not been well investigated. We report that both the presence of activated macrophages and the formation of lymphatic vessels are rate-limiting to the… CONTINUE READING