Decreased levels of serum brain-derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disorders.

@article{Monteleone2008DecreasedLO,
  title={Decreased levels of serum brain-derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disorders.},
  author={Palmiero Monteleone and Cristina Serritella and Vassilis Martiadis and Mario Maj},
  journal={Bipolar disorders},
  year={2008},
  volume={10 1},
  pages={95-100}
}
OBJECTIVES Brain-derived neurotrophic factor (BDNF) has been proposed as a candidate molecule in the pathophysiology of major depressive disorder (MDD) and bipolar disorders (BD). Reduced levels of peripheral BDNF have been found in drug-free MDD patients, in drug-treated depressed or manic patients with BD type I (BD-I), but not in drug-treated euthymic BD-I individuals. No study has been done in patients with BD type II (BD-II). Moreover, the influence of Axis I psychiatric comorbidity on… CONTINUE READING

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[The anatomy of depression in light of evidence from neuroimaging studies].

Psychiatria polska • 2008
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