Decreased levels of miR-34a and miR-217 act as predictor biomarkers of aggressive progression and poor prognosis in hepatocellular carcinoma.

@article{Tian2017DecreasedLO,
  title={Decreased levels of miR-34a and miR-217 act as predictor biomarkers of aggressive progression and poor prognosis in hepatocellular carcinoma.},
  author={Yu-wei Tian and Q. Shen and Qing-feng Jiang and Yao-Xuan Wang and K. Li and Huan-zhou Xue},
  journal={Minerva medica},
  year={2017},
  volume={108 2},
  pages={
          108-113
        }
}
  • Yu-wei Tian, Q. Shen, +3 authors Huan-zhou Xue
  • Published 2017
  • Medicine
  • Minerva medica
  • BACKGROUND MicroRNAs (miRNAs) play key roles in tumor development and progression. The aim of this study was to explore the expression levels of miR-34a and miR-217 in hepatocellular carcinoma (HCC) and to further investigate the clinicopathological and prognostic value of miR-34a and miR-217. METHODS The expression levels of miR-34a and miR-217 were evaluated using quantitative real-time PCR (qRT-PCR). Associations between these miRNAs expression and clinicopathological features were… CONTINUE READING
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