Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin?

@article{Imokawa1991DecreasedLO,
  title={Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin?},
  author={Genji Imokawa and Akio Abe and Ke-wei Jin and Yuko Higaki and Makoto Kawashima and A. Hidano},
  journal={The Journal of investigative dermatology},
  year={1991},
  volume={96 4},
  pages={523-6}
}
Stratum corneum lipids are an important determinant for both water-retention function and permeability-barrier function in the stratum corneum. However, their major constituent, ceramides, have not been analyzed in detail in skin diseases such as atopic dermatitis that show defective water-retention and permeability-barrier function. In an attempt to assess the quantity of ceramides per unit mass of the stratum corneum in atopic dermatitis, stratum corneum sheet was removed from the forearm… CONTINUE READING
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