Decreased intercellular communication and connexin expression in mouse aortic endothelium during lipopolysaccharide-induced inflammation.

@article{Simon2004DecreasedIC,
  title={Decreased intercellular communication and connexin expression in mouse aortic endothelium during lipopolysaccharide-induced inflammation.},
  author={Alexander M. Simon and Andrea R. McWhorter and Hwudaurw Chen and Charity L Jackson and Yves Ouellette},
  journal={Journal of vascular research},
  year={2004},
  volume={41 4},
  pages={323-33}
}
The role of gap junctional intercellular communication during inflammatory processes is not well understood. In particular, changes in the expression and function of vascular endothelial connexins (gap junction proteins) in response to inflammatory agents has not been fully investigated. In this study, we used intercellular dye transfer methods to assess interendothelial communication in aortic segments isolated from mice treated with or without intraperitoneal lipopolysaccharide (LPS), a… CONTINUE READING

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