Decreased insulin binding of human erythrocytes after dexamethasone or prednisone ingestion.

@article{Yasuda1980DecreasedIB,
  title={Decreased insulin binding of human erythrocytes after dexamethasone or prednisone ingestion.},
  author={Koichiro Yasuda and Abbas E. Kitabchi},
  journal={Diabetes},
  year={1980},
  volume={29 10},
  pages={811-4}
}
We have investigated changes in insulin binding in erythrocytes in response to overnight ingestion of 1 mg dexamethasone or 10 mg of prednisone in two groups of eight lean, healthy subjects. Dexamethasone administration reduced insulin binding from 9.6 to 6.8% (P < 0.001) with concomitant increase in basal plasma insulin from 10.5 to 14.1 microU/ml (P < 0.05). Prednisone ingestion reduced insulin binding from 9.9 to 7.9% (P < 0.01), but the increase in basal insulin from 16.9 to 20.6 microU/ml… CONTINUE READING

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