Decreased hepatic peroxisome proliferator-activated receptor-γ contributes to increased sensitivity to endotoxin in obstructive jaundice.

Abstract

AIM To investigate the role of hepatic peroxisome proliferator-activated receptor-γ (PPAR-γ) in increased susceptibility to endotoxin-induced toxicity in rats with bile duct ligation during endotoxemia. METHODS Male Sprague-Dawley rats were subjected to bile duct ligation (BDL). Sham-operated animals served as controls. DNA binding were determined by… (More)
DOI: 10.3748/wjg.v17.i48.5267

Topics

Cite this paper

@article{Lv2011DecreasedHP, title={Decreased hepatic peroxisome proliferator-activated receptor-γ contributes to increased sensitivity to endotoxin in obstructive jaundice.}, author={Xin Lv and Jian-gang Song and Hong-hai Li and Jun-ping Ao and Ping Zhang and Ye-sheng Li and Shaoli Song and Xiang-Rui Wang}, journal={World journal of gastroenterology}, year={2011}, volume={17 48}, pages={5267-73} }