Decreased gray matter volume in the left middle temporal gyrus as a candidate biomarker for schizophrenia: A study of drug naive, first-episode schizophrenia patients and unaffected siblings

@article{Guo2014DecreasedGM,
  title={Decreased gray matter volume in the left middle temporal gyrus as a candidate biomarker for schizophrenia: A study of drug naive, first-episode schizophrenia patients and unaffected siblings},
  author={Wenbin Guo and Maorong Hu and X Fan and Feng Liu and Jingping Zhao},
  journal={Schizophrenia Research},
  year={2014},
  volume={159},
  pages={43-50}
}
BACKGROUND Studies have shown that patients with schizophrenia and their siblings share decreased gray matter (GM) volumes in certain brain regions, which may represent candidate endophenotypes of schizophrenia. However, the specificity and utility of these possible endophenotypes in relation to schizophrenia remain unclear. METHODS Twenty drug-naive, first-episode schizophrenia patients and 20 first-degree unaffected siblings from the same families as the patients (USS group), a separate… CONTINUE READING
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