Decreased gastric tone and delayed gastric emptying precede neutrophil infiltration and mucosal lesion formation in indomethacin-induced gastric damage in rats.

@article{Souza2003DecreasedGT,
  title={Decreased gastric tone and delayed gastric emptying precede neutrophil infiltration and mucosal lesion formation in indomethacin-induced gastric damage in rats.},
  author={Marcellus Henrique Loiola Ponte Souza and Luiz Ernesto de Almeida Troncon and Fernando Q Cunha and R B de Oliveira},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2003},
  volume={36 10},
  pages={1383-90}
}
Gastric antral dysmotility has been implicated in the pathogenesis of indomethacin-induced gastric damage, but the relationship between gastric motor abnormalities and mucosal lesions has not been extensively studied. We investigated whether changes in gastric tone and gastric retention correlate with mucosal lesions and neutrophil migration in indomethacin… CONTINUE READING