Decreased frontal serotonin 5-HT2a receptor binding index in deliberate self-harm patients

  title={Decreased frontal serotonin 5-HT2a receptor binding index in deliberate self-harm patients},
  author={Kurt R Audenaert and Koen Van Laere and Filip Dumont and Guido Slegers and John D. Mertens and Cees van Heeringen and Rudi A. Dierckx},
  journal={European Journal of Nuclear Medicine},
Studies of serotonin metabolites in body fluids in attempted suicide patients and of post-mortem brain tissue of suicide victims have demonstrated the involvement of the serotonergic neurotransmission system in the pathogenesis of suicidal behaviour. Recently developed neuroimaging techniques offer the unique possibility of investigating in vivo the functional characteristics of this system. In this study the 5-HT2a receptor population of patients who had recently attempted suicide was studied… CONTINUE READING
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