Decreased fluidity of isolated erythrocyte membranes in type 1 and type 2 diabetes. The effect of resorcylidene aminoguanidine.

@article{Waczulkov2000DecreasedFO,
  title={Decreased fluidity of isolated erythrocyte membranes in type 1 and type 2 diabetes. The effect of resorcylidene aminoguanidine.},
  author={Iveta Waczul{\'i}kov{\'a} and Libu{\vs}a {\vS}ikurov{\'a} and Jozef {\vC}{\'a}rsky and Lujza Strbova and Boris Krahulec},
  journal={General physiology and biophysics},
  year={2000},
  volume={19 4},
  pages={381-92}
}
Changes in the physico-chemical properties of erythrocyte membranes induced by nonenzymatic glycation as well as the possible prevention of their rise were studied. Using the fluorescent probe 1,6-diphenyl-1,3,5-hexatriene (DPH), fluorescence anisotropy values were determined in erythrocyte membranes isolated from type 1 and type 2 diabetic patients with and without complications. The mean anisotropy values for the groups of diabetic patients were significantly higher than those for the control… CONTINUE READING