Decreased expression of the mRNA for somatostatin in the periventricular nucleus of depression-model rats.

@article{Zhang1999DecreasedEO,
  title={Decreased expression of the mRNA for somatostatin in the periventricular nucleus of depression-model rats.},
  author={K. Zhang and K. Hamanaka and I. Kitayama and H. Soya and H. Yoshizato and S. Nakase and Y. Uesugi and K. Inui and J. Nomura and Y. Okazaki},
  journal={Life sciences},
  year={1999},
  volume={65 9},
  pages={
          PL87-94
        }
}
Expression of the mRNA for somatostatin (SRIF) in the periventricular nucleus (PeN), the level of SRIF in the stalk-median eminence (SME) and the concentration of growth hormone (GH) in the plasma were examined in depression-model rats in an attempt to confirm the hypothesis that SRIF neurons in the hypothalamus are hypofunctional in this model. We exposed male Wistar rats to intermittent walking stress for two weeks and then we measured their spontaneous running activity for 12 days. We… Expand
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