Decreased expression of catenins (alpha and beta), p120 CTN, and E-cadherin cell adhesion proteins and E-cadherin gene promoter methylation in prostatic adenocarcinomas.

Abstract

BACKGROUND Catenin/E-cadherin complex proteins play an important role in cell-cell adhesion with decreased expression correlating with adverse prognostic variables in several human malignancies. METHODS Archival formalin fixed, paraffin embedded (FFPE) sections from 118 prostatic adenocarcinomas (PACs) were immunostained by an automated method (Ventana… (More)

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@article{Kallakury2001DecreasedEO, title={Decreased expression of catenins (alpha and beta), p120 CTN, and E-cadherin cell adhesion proteins and E-cadherin gene promoter methylation in prostatic adenocarcinomas.}, author={Bhaskar Kallakury and Chelsea Sheehan and E. Winn-Deen and J. Oliver and Heinrich Fisher and R. Perlman C. Kaufman and Jeffrey S Ross}, journal={Cancer}, year={2001}, volume={92 11}, pages={2786-95} }