Decreased expression of aquaporin (AQP)1 and AQP5 in mouse lung after acute viral infection.

@article{Towne2000DecreasedEO,
  title={Decreased expression of aquaporin (AQP)1 and AQP5 in mouse lung after acute viral infection.},
  author={Jennifer E Towne and Kevin S. Harrod and Carissa M. Krane and Anil G. Menon},
  journal={American journal of respiratory cell and molecular biology},
  year={2000},
  volume={22 1},
  pages={34-44}
}
Intratracheal infection of mice with adenovirus is associated with subsequent pulmonary inflammation and edema. Water movement through the air space-capillary barrier in the distal lung is facilitated by aquaporins (AQPs). To investigate the possibility that distal lung AQPs undergo altered regulation under conditions of aberrant fluid handling in the lung, we analyzed messenger RNA (mRNA) and protein expression of AQPs 1 and 5 in the lungs of mice 7 and 14 d after infection with adenovirus… CONTINUE READING