Decreased expression of an ATP-binding cassette transporter, MRP2, in human livers with hepatitis C virus infection.

@article{Hinoshita2001DecreasedEO,
  title={Decreased expression of an ATP-binding cassette transporter, MRP2, in human livers with hepatitis C virus infection.},
  author={Eiji Hinoshita and K Taguchi and Akihiko Inokuchi and Takeshi Uchiumi and Naoko Kinukawa and Mitsuo Shimada and Masazumi Tsuneyoshi and Keizo Sugimachi and Michihiko Kuwano},
  journal={Journal of hepatology},
  year={2001},
  volume={35 6},
  pages={765-73}
}
BACKGROUND/AIMS To understand hepatic injury during the process of hepatitis viral infection, determination of liver-specific functions at molecular levels is critical. Because the transport of endogenous/exogenous toxic substances is an intrinsically important hepatic function, we examined whether expression of the ATP-binding cassette (ABC) transporter gene was affected in patients with hepatitis viral infection. METHODS To determine which ABC transporter was expressed differently in… CONTINUE READING