Decreased expression of adhesion molecules on monocytes in recent onset IDDM.

@article{Martin1991DecreasedEO,
  title={Decreased expression of adhesion molecules on monocytes in recent onset IDDM.},
  author={Stephan Martin and Helga Rothe and Diethelm Tschoepe and B. Schwippert and Helmut J. Kolb},
  journal={Immunology},
  year={1991},
  volume={73 1},
  pages={123-5}
}
The expression of adhesion molecules in monocytes of patients with recent onset type I diabetes was analysed. Monocytes were identified as CD14-positive cells by flow cytometry. The percentage of monocytes expression LFA-1 alpha, ICAM-1 and HLA-DR was slightly lower in recent onset type I diabetes (n = 13) compared to normal subjects (n = 15) and was significantly decreased after activation of cells with lipopolysaccharide and interferon-gamma for 5-24 hr. Receptor densities on adhesion… CONTINUE READING