Decreased expression of TGF-beta type II receptor in bronchial glands of smokers with COPD.

@article{Baraldo2005DecreasedEO,
  title={Decreased expression of TGF-beta type II receptor in bronchial glands of smokers with COPD.},
  author={Simonetta Baraldo and Erica Bazzan and Graziella Turato and Francesca Calabrese and Bianca Begh{\'e} and Alberto Papi and Piero Maestrelli and Leonardo M Fabbri and Renzo Zuin and Marina Saetta},
  journal={Thorax},
  year={2005},
  volume={60 12},
  pages={
          998-1002
        }
}
BACKGROUND The role of transforming growth factor-beta1 (TGF-beta1) in chronic obstructive pulmonary disease is still controversial, but it has been proposed that it may protect from mucus hypersecretion since it is able to downregulate mucin production. A study was undertaken to investigate the expression of TGF-beta1 and its type II receptor (TGF-beta RII) in the bronchial glands of smokers with COPD. METHODS The expression of TGF-beta(1) and TGF-beta RII were examined immunohistochemically… CONTINUE READING

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Decreased expression of TGFβ1 type II receptor in bronchial glands of smokers with COPD

  • S Baraldo, E Bazzan, +8 authors M. Saetta
  • Eur Respir J
  • 2004
Highly Influential
6 Excerpts

Downregulation of transforming growth factor β type II receptor (TGFβ−RII) in bronchial glands of smokers with chronic bronchitis

  • S Baraldo, E Bazzan, +8 authors M. Saetta
  • Am J Respir Crit Care Med
  • 2004
Highly Influential
6 Excerpts

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