Decreased cutaneous vasodilatation to isometric handgrip exercise in Alzheimer's disease.

@article{Klmn2002DecreasedCV,
  title={Decreased cutaneous vasodilatation to isometric handgrip exercise in Alzheimer's disease.},
  author={J{\'a}nos K{\'a}lm{\'a}n and R{\'e}ka Szak{\'a}cs and Tam{\'a}s T{\"o}r{\"o}k and Zsuzsa R{\'o}zsa and P{\'a}l Barz{\'o} and L{\'a}szl{\'o} Rudas and Julius Gy Papp and Zolt{\'a}n Janka},
  journal={International journal of geriatric psychiatry},
  year={2002},
  volume={17 4},
  pages={371-4}
}
BACKGROUND Cutaneous active vasodilatation is a cholinergic nerve mediated function of the sympathetic nervous system and the disturbed function of cholinergic neurotransmission is known as a prominent feature of Alzheimer's disease (AD). METHODS To assess this relationship, skin blood flow (SkBF) and other haemodynamic parameters were determined by a simple vasodilatory test, isometric handgrip exercise (IHG), in 22 late-onset sporadic type AD and 20 aged control persons (AC). RESULTS… CONTINUE READING