Decreased creatine kinase is linked to diastolic dysfunction in rats with right heart failure induced by pulmonary artery hypertension

@inproceedings{Fowler2015DecreasedCK,
  title={Decreased creatine kinase is linked to diastolic dysfunction in rats with right heart failure induced by pulmonary artery hypertension},
  author={Ewan D Fowler and David Benoist and Mark J. Drinkhill and Rachel Stones and Michiel Helmes and Rob C I W{\"u}st and Ger J M Stienen and Derek Steele and Ed White},
  booktitle={Journal of molecular and cellular cardiology},
  year={2015}
}
Our objective was to investigate the role of creatine kinase in the contractile dysfunction of right ventricular failure caused by pulmonary artery hypertension. Pulmonary artery hypertension and right ventricular failure were induced in rats by monocrotaline and compared to saline-injected control animals. In vivo right ventricular diastolic pressure-volume relationships were measured in anesthetized animals; diastolic force-length relationships in single enzymatically dissociated myocytes and… CONTINUE READING
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