Decreased cortical glucose metabolism correlates with hippocampal atrophy in Alzheimer's disease as shown by MRI and PET.

@article{Yamaguchi1997DecreasedCG,
  title={Decreased cortical glucose metabolism correlates with hippocampal atrophy in Alzheimer's disease as shown by MRI and PET.},
  author={Satoru Yamaguchi and Kenichi Meguro and Masatoshi Itoh and Chika Hayasaka and Masumi Shimada and Hisato Yamazaki and Atsushi Yamadori},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={1997},
  volume={62 6},
  pages={596-600}
}
OBJECTIVE To investigate the relation between atrophy of the hippocampus and parahippocampal gyrus (the % hippocampal area) and cerebral metabolic rate for glucose (CMRGlc) in Alzheimer's disease. METHODS 13 patients with probable Alzheimer's disease by NINCDS-ADRDA criteria (six men; seven women, mean age 71 years, mini mental state 13.8 (SD 4.6)) and age matched controls were studied. T1 weighted MRI (0.5T) images were used for evaluation of the hippocampal area. With a digitiser system, a… CONTINUE READING

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