Decreased contractile response after exposure of the rat aorta to Db cAMP or IBMX.

@article{Warbanow1987DecreasedCR,
  title={Decreased contractile response after exposure of the rat aorta to Db cAMP or IBMX.},
  author={W Warbanow and Liane Will-Shahab},
  journal={Biomedica biochimica acta},
  year={1987},
  volume={46 8-9},
  pages={S477-81}
}
Isometric tension developed by different receptor agonists was found to be decreased after pretreatment of rat aortic rings with IBMX or Db cAMP and only partially restored by CaCl2 and A 23187. The contraction produced by Bay k 8644 was converted into dose-dependent relaxation after pretreatment of the aorta rings with Db cAMP or IBMX. An alteration of the calcium channel is assumed to play a common role in the cAMP-dependent inhibition of the smooth muscle contraction. 

From This Paper

Topics from this paper.
1 Citations
0 References
Similar Papers

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…