Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[(11)C]DASB and structural brain imaging study.

@article{Kish2010DecreasedCC,
  title={Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[(11)C]DASB and structural brain imaging study.},
  author={Stephen J. Kish and J. A. Lerch and Yoshiaki Furukawa and Junchao Tong and Tina McCluskey and Diana G. Wilkins and Sylvain Houle and Jeffrey H. Meyer and Emanuela Mundo and Alan A. Wilson and Pablo M Rusjan and Jean A. Saint-Cyr and Mark Guttman and D. Louis Collins and Colin Shapiro and Jerry J. Warsh and Isabelle Boileau},
  journal={Brain : a journal of neurology},
  year={2010},
  volume={133 Pt 6},
  pages={1779-97}
}
Animal data indicate that the recreational drug ecstasy (3,4-methylenedioxymethamphetamine) can damage brain serotonin neurons. However, human neuroimaging measurements of serotonin transporter binding, a serotonin neuron marker, remain contradictory, especially regarding brain areas affected; and the possibility that structural brain differences might account for serotonin transporter binding changes has not been explored. We measured brain serotonin transporter binding using [(11)C] N,N… CONTINUE READING
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