Decreased cardiolipin synthesis corresponds with cytochrome c release in palmitate-induced cardiomyocyte apoptosis.

@article{Ostrander2001DecreasedCS,
  title={Decreased cardiolipin synthesis corresponds with cytochrome c release in palmitate-induced cardiomyocyte apoptosis.},
  author={Darin B Ostrander and Genevieve C. Sparagna and Andrew A. Amoscato and Jeanie B. McMillin and William Dowhan},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 41},
  pages={38061-7}
}
Apoptosis has been identified recently as a component of many cardiac pathologies. However, the potential triggers of programmed cell death in the heart and the involvement of specific metabolic pathway(s) are less well characterized. Detachment of cytochrome c from the mitochondrial inner membrane is a necessary first step for cytochrome c release into the… CONTINUE READING