Decreased blood flow rate disrupts endothelial repair in vivo.

@article{Vyalov1996DecreasedBF,
  title={Decreased blood flow rate disrupts endothelial repair in vivo.},
  author={S. L. Vyalov and B. Lowell Langille and Avrum I. Gotlieb},
  journal={The American journal of pathology},
  year={1996},
  volume={149 6},
  pages={2107-18}
}
Both local hemodynamics and endothelial injury have been implicated in vascular disorders including bypass graft failure and atherogenesis, but little is known about the effect of local blood flow conditions on repair of endothelial injury. We decreased blood flow rates and shear stresses in common carotid arteries of rabbits by ligating the ipsilateral… CONTINUE READING