Decreased behavioral activation following caffeine, amphetamine and darkness in A3 adenosine receptor knock-out mice.

@article{Bjrklund2008DecreasedBA,
  title={Decreased behavioral activation following caffeine, amphetamine and darkness in A3 adenosine receptor knock-out mice.},
  author={Olga Bj{\"o}rklund and Linda Halldner-Henriksson and Jiangning Yang and Therese M. Eriksson and Marlene A. Jacobson and Elisabetta Dar{\'e} and Bertil B. Fredholm},
  journal={Physiology & behavior},
  year={2008},
  volume={95 5},
  pages={668-76}
}
We have examined behavioral consequences of genetic deletion of the adenosine A3 receptors in mice. The open field behavior of A3 adenosine receptor knock-out (A3R KO) mice was investigated both under basal conditions and after stimulation with psychostimulants. Adolescent (21 day-old) and adult A3R KO males showed an increase in overall motor activity… CONTINUE READING