Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease.

@article{Scher2015DecreasedBD,
  title={Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease.},
  author={Jose U. Scher and Carles {\'U}beda and Alejandro Artacho and Mukundan G. Attur and Sandrine Isaac and S Madhusudana Reddy and Shoshana Marmon and Andrea L Neimann and Samuel B. Brusca and Tejas Patel and Julia Manasson and Eric G. Pamer and Dan R. Littman and Steven B. Abramson},
  journal={Arthritis & rheumatology},
  year={2015},
  volume={67 1},
  pages={128-39}
}
OBJECTIVE To characterize the diversity and taxonomic relative abundance of the gut microbiota in patients with never-treated, recent-onset psoriatic arthritis (PsA). METHODS High-throughput 16S ribosomal RNA pyrosequencing was utilized to compare the community composition of gut microbiota in patients with PsA (n = 16), patients with psoriasis of the skin (n = 15), and healthy, matched control subjects (n = 17). Samples were further assessed for the presence and levels of fecal and serum… CONTINUE READING
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