Decreased aminotransferase activity of serum and various tissues in the rat after cefazolin treatment.

@article{Dhami1979DecreasedAA,
  title={Decreased aminotransferase activity of serum and various tissues in the rat after cefazolin treatment.},
  author={Mandeep S Dhami and R Drangova and Ruth Farkas and Tania C Balazs and Gerold Feuer},
  journal={Clinical chemistry},
  year={1979},
  volume={25 7},
  pages={1263-6}
}
Treatment of rats with cefazolin in vivo significantly suppressed activity of alanine and aspartate aminotransferases in serum and in the liver, brain, kidney, and heart. Simultaneous administration of pyridoxal further reduced enzyme activity except in the liver, where there was no change. Pyridoxal 5'-phosphate partly reversed the decreased enzyme activity in the serum, liver, and kidney, but did not return it to the amount observed in the control animals; enzyme activity remained suppressed… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 15 references

Statistical Methods , 5 th ed . , Iowa State Uni - phosphate of aspartate transaminase in serum of patients with heart versity Press , Ames , IA , 1956 . and liver disease

S. B. Rosalki, R. A. Bayoumi, G. W. Snedecor
Clin . Chim . Acta • 1975

Pharmacology Review of IND 8136, sponsored by Smith, Kline and French Laboratories. Bureau of Drug, Food and Drug Administration, Dept

G. W. James
1971
View 1 Excerpt

Schiff base intermediate in enzyme catalysis

E. E. Snell, S. J. Di Man
In The Enzymes, • 1970
View 1 Excerpt

The effects of drugs on laboratory

M. Lubran
values. Med. Clin. NorthAm • 1969
View 1 Excerpt

The effects of drugs on laboratory values

M. Lubran
Med . Clin . NorthAm . • 1969

Some changes in the serum during treatment with psychotropic drugs.

The Journal of nervous and mental disease • 1966
View 1 Excerpt

Similar Papers

Loading similar papers…