Decreased acute rejection and improved renal allograft survival using sirolimus and low-dose calcineurin inhibitors without induction therapy.

Abstract

BACKGROUND Chronic nephrotoxicity of calcineurin inhibitors (CNIs) causes irreversible renal dysfunction and shortens renal transplant survival. We conducted a retrospective cohort study to test a hypothesis that de novo CNI minimization combined with sirolimus (SRL) improves graft survival in renal transplant patients without antibody induction therapy… (More)

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@article{Tsai2009DecreasedAR, title={Decreased acute rejection and improved renal allograft survival using sirolimus and low-dose calcineurin inhibitors without induction therapy.}, author={Meng-Kun Tsai and F. L. Wu and I R Lai and Chih-Yuan Lee and R H Hu and Po-huang Lee}, journal={The International journal of artificial organs}, year={2009}, volume={32 6}, pages={371-80} }