Decreased activity of liver glutathione peroxidase in human hepatocellular carcinoma.

@article{Casaril1985DecreasedAO,
  title={Decreased activity of liver glutathione peroxidase in human hepatocellular carcinoma.},
  author={Massimo Casaril and Giovanni Battista Gabrielli and Stefano Dusi and Nicola Nicoli and Giuseppe Bellisola and Roberto Corrocher},
  journal={European journal of cancer & clinical oncology},
  year={1985},
  volume={21 8},
  pages={
          941-4
        }
}
Glutathione peroxidase (GSH-Px) activity, one of the scavenger enzymes of oxygen active radicals, has been measured in hepatocellular carcinoma (HCC) of 17 patients and the values compared with the activity of adjacent tumor-free tissue and with those of 30 histologically normal livers. The results demonstrate a reduced GSH-Px activity in neoplastic tissue (21.19 vs 33.74 U/g prot.; P less than 0.001). However, the adjacent tumor-free liver also had a reduced activity when compared with normal… CONTINUE READING
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