Decreased Resting Functional Connectivity after Traumatic Brain Injury in the Rat

@inproceedings{Mishra2014DecreasedRF,
  title={Decreased Resting Functional Connectivity after Traumatic Brain Injury in the Rat},
  author={Asht M. Mishra and Xiaoxiao Bai and Basavaraju G. Sanganahalli and Stephen G. Waxman and Olena Shatillo and Olli H.J. Grohn and Fahmeed Hyder and A. S. L. Pitk{\"a}nen and Hal Blumenfeld},
  booktitle={PloS one},
  year={2014}
}
Traumatic brain injury (TBI) contributes to about 10% of acquired epilepsy. Even though the mechanisms of post-traumatic epileptogenesis are poorly known, a disruption of neuronal networks predisposing to altered neuronal synchrony remains a viable candidate mechanism. We tested a hypothesis that resting state BOLD-fMRI functional connectivity can reveal network abnormalities in brain regions that are connected to the lesioned cortex, and that these changes associate with functional impairment… CONTINUE READING

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