Decreased NKCC1 activity in erythrocytes from African Americans with hypertension and dyslipidemia.

BACKGROUND Recent studies demonstrated a key role of ubiquitous isoform of Na+,K+,2Cl- co-transport (NKCC1) in regulation of myogenic tone and peripheral resistance. We examined the impact of race, gender, and plasma lipid on NKCC1 activity in French Canadians and African Americans with hypertension and dyslipidemia. METHODS NKCC and passive erythrocyte… CONTINUE READING