Decreased IH in hippocampal area CA1 pyramidal neurons after perinatal seizure-inducing hypoxia.

Abstract

PURPOSE The hyperpolarization-activated cation current (IH) has been proposed to play a role in some forms of epileptogenesis, as it critically regulates synaptic integration and intrinsic excitability of principal limbic neurons and can be pathologically altered after experimentally induced seizures. In hippocampal CA1 pyramidal neurons, IH is functionally… (More)

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