Decreased Glutamatergic Activity in the Frontal Cortex of Single Prolonged Stress Model: In vivo and Ex Vivo Proton MR Spectroscopy

@article{Lim2017DecreasedGA,
  title={Decreased Glutamatergic Activity in the Frontal Cortex of Single Prolonged Stress Model: In vivo and Ex Vivo Proton MR Spectroscopy},
  author={Song-I Lim and Kyu-Ho Song and Chi-Hyeon Yoo and Dong-Cheol Woo and Bo-Young Choe},
  journal={Neurochemical Research},
  year={2017},
  volume={42},
  pages={2218-2229}
}
Single prolonged stress (SPS) is one of the preclinical models of posttraumatic stress disorder (PTSD) in humans. Not every traumatized person develops PTSD and the onset of the disease varies from months to many years after exposure to life-threatening events. The pathogenetic neurometabolites in PTSD have not been investigated to date, and could provide a means for therapeutic interventions. Therefore the present study aimed to evaluate neurochemical changes in the frontal cortex in the SPS… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 46 REFERENCES

Brain metabolic alterations in mice subjected to postnatal traumatic stress and in their offspring

  • Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
  • 2017
VIEW 2 EXCERPTS