Decreased Frequencies of Circulating Follicular Helper T Cell Counterparts and Plasmablasts in Ankylosing Spondylitis Patients Naïve for TNF Blockers

@inproceedings{BautistaCaro2014DecreasedFO,
  title={Decreased Frequencies of Circulating Follicular Helper T Cell Counterparts and Plasmablasts in Ankylosing Spondylitis Patients Na{\"i}ve for TNF Blockers},
  author={Mar{\'i}a-Bel{\'e}n Bautista-Caro and Irene Arroyo-Villa and Concepci{\'o}n Castillo-Gallego and Eugenio de Miguel and Diana Peiteado and Chamaida Plasencia-Rodr{\'i}guez and Alejandro Villalba and Paloma S{\'a}nchez-Mateos and Amaya Puig-Kr{\"o}ger and Emilio Mart{\'i}n-Mola and Mar{\'i}a-Eugenia Miranda-Car{\'u}s},
  booktitle={PloS one},
  year={2014}
}
Follicular helper T cells (Tfh), localized in lymphoid organs, promote B cell differentiation and function. Circulating CD4 T cells expressing CXCR5, ICOS and/or PD-1 are counterparts of Tfh. Three subpopulations of circulating CD4+CXCR5+ cells have been described: CXCR3+CCR6- (Tfh-Th1), CXCR3-CCR6+ (Tfh-Th17), and CXCR3-CCR6- (Tfh-Th2). Only Tfh-Th17 and Tfh-Th2 function as B cell helpers. Our objective was to study the frequencies of circulating Tfh (cTfh), cTfh subsets and plasmablasts (CD19… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

T Follicular Helper Cells in Autoimmune Disorders

  • Front. Immunol.
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

Decreased PD-1 positive blood follicular helper T cells in patients with psoriasis

  • Archives of Dermatological Research
  • 2016
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 51 REFERENCES

Autoantibodies against CD74 in spondyloarthritis.

  • Annals of the rheumatic diseases
  • 2014
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL