Decreased Concentrations of Tumor Necrosis Factor-a in Supernatants of Monocytes From Homozygotes for Hereditary Hemochromatosis

To determine whether release of tumor necrosis factor-a (TNF-a), a cytokine that affects iron homeostasis, may be selectively altered in hereditary hemochromatosis, we measured concentrations of TNF-a and interleukin-ls (IL-ls) in supernatants of cultured peripheral blood monocytes from 11 homozygotes for hereditary hemochromatosis, 11 healthy individuals… (More)