Decreased BDNF levels in CSF of drug-naive first-episode psychotic subjects: correlation with plasma BDNF and psychopathology.

@article{Pillai2010DecreasedBL,
  title={Decreased BDNF levels in CSF of drug-naive first-episode psychotic subjects: correlation with plasma BDNF and psychopathology.},
  author={Anilkumar Pillai and Anvita Anand Kale and Sadhana R Joshi and Nilesh S Naphade and M. S. V. K. Raju and Henry A Nasrallah and Sahebarao Prabhu Mahadik},
  journal={The international journal of neuropsychopharmacology},
  year={2010},
  volume={13 4},
  pages={535-9}
}
Brain-derived neurotrophic factor (BDNF), which plays an important role in neurodevelopmental plasticity and cognitive performance, has been implicated in neuropsychopathology of schizophrenia. We examined the levels of both cerebrospinal fluid (CSF) and plasma BDNF concomitantly in drug-naive first-episode psychotic (FEP) subjects with ELISA to determine if these levels were different from control values and if any correlation exists between CSF and plasma BDNF levels. A significant reduction… CONTINUE READING

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Cell biology of BDNF and its relevance to schizophrenia.

Novartis Foundation symposium • 2008
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